A hypoallergenic cat is a cat, which is less likely to provoke an allergic reaction in humans. Research has shown that all cats produce Fel d 1, however some cats produce considerably less than others. The Siberian Cat breed is thought to produce the lowest levels of Fel d 1. The University of California Davis and Siberian Research Inc. has begun measuring Fel d 1 levels in fur and saliva in kittens as young as 9-12 weeks of age.

However, some individuals allergic to Fel d1 will still react to the Siberian breed. Whether there is an allergic reaction or not will depend on the severity of the allergy and the level of Fel d1 produced by the particular Siberian Cat. It may also depend on the time of year and the amount of other allergens the allergic person comes in contact with.